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The use of a drug to get high is abuse of that drug: "There is no such thing as use without abuse in intoxicating substances."8] In an essay in what is widely considered the bible of clinical pharmacology, the following is a definition of drug abuse (of which marijuana abuse is discussed as an instance; a distinction is made between obsolete "Therapeutic Uses" and current "Patterns of Abuse"): In this chapter, the term "drug abuse" will be used in its broadest sense, to refer to use, usually by self-administration, of any drug in a manner that deviates from the approved medical or social patterns within a given culture. So defined, the term rightfully includes the "misuse" of a wide spectrum of drugs.... However, attention will be directed to the abuse of drugs that produce changes in mood and behavior.9] Etiology of Drug Use In terms of the etiology of marijuana use, physicians may generally be found within the orbit of the personality theory of causality. Now, no psychologist or psychiatrist would dispute the contention that sociological factors play a decisive role in marijuana use. Clearly, a milieu wherein marijuana is totally lacking, or in which its use is savagely condemned, is not likely to generate many marijuana smokers, regardless of the psychological predisposition of the individuals within that ambiance. Yet, at the same time, a theory of marijuana use set forth by a psychologist, psychiatrist, or physician, will look and sound very different from one delineated by a sociologist. Doctors will tend to emphasize individual and motivational factors in the etiology of marijuana use. It is necessary, therefore, according to this perspective, to understand the individual's life history, particularly his early family relations, if we are to understand why an individual does as he does, particularly if he challenges the established social order—as, to some degree, his use of marijuana does. An individual of a certain family background will be predisposed to specific certain kinds of behavior. (6 of 25)4/15/2004 1:04:59 AM The Marijuana Smokers - Chapter 5 More than merely being generated to a considerable degree by personality factors, physicians (following psychologists and psychiatrists) often see marijuana use as being at least to some degree generated by pathological or abnormal motives. Sometimes this is seen as a general process; marijuana use, like all illicit, deviant, and illegal drug use, represents a form of neurosis, however mild: "The willingness of a person to take drugs may represent a defect of a superego functioning in itself."10] It is, of course, necessary to specify the degree of drug involvement. Most physicians will not view occasional or experimental use in the same light as frequent, habitual, or "chronic" marijuana use. 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